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Edosuyi, O., Omo-Erhabor, A.J., Great-Nelson, K., Ogbuehi, B.A., Onyeukwu, N.O., Oluwasemilore, A.F., Emmanuel, 2Olorundare T., Winifred, A., Edosuyi, V. and Igbe, I. 2026. Assessing novel antinociceptive mechanisms and anxiolytic effects of a combination of orphenadrine and diclofenac in experimental mice: In silico, molecular and histological perspectives. Nigerian Journal of Pharmaceutical and Applied Science Research. 15, 1 (Apr. 2026), 8–17. DOI:https://doi.org/10.60787/nijophasr-v15-i1-641.